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Nature Medicine:一种新的多基因风险评分,找到从降胆固醇疗法中获益 ...
研究团队识别了35个与内皮细胞功能和冠状动脉疾病相关的单核苷酸多态性——单个“字母”遗传变化,并据此创建了一个风险评分,随后在三个独立研究人群中对参与者进行随访以进行预测。他们发现,内皮细胞风险较高的个体从LDL-C降低疗法中获益颇丰,且该评分可用于预测冠状动脉疾病风险。
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