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6 天
营养与健康所姚依昆研究组合作发现在翻译水平调控T细胞死亡的关键 ...
研究人员利用流式细胞术、免疫印迹及一系列功能实验验证了敲除AMBRA1能够降低FAS蛋白表达,抑制FAS途径诱导的T细胞凋亡。进一步的机制探究中,研究人员利用OPP掺入结合点击化学,蔗糖梯度离心分离核糖体及其结合的mRNA等手段,发现AMBRA1促进 ...
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